Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Nitrobenzenesulfonyl chloride → N-cyclopropyl-2-nitrobenzenesulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Nitrobenzenesulfonyl chloride | HCID 15540 | — |
| 반응물 | Cyclopropylamine | HCID 69828 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | N-cyclopropyl-2-nitrobenzenesulfonamide | HCID 796630 | 88% |
반응 단계
To a −78° C. mixture of cyclopropylamine (10 g, 1.75 mmol) in CH2Cl2 (100 mL) was added a solution of 2-nitrobenzene sulfonyl chloride (22.1 g, 85.7 mmol) and the mixture was stirred for 12 h. The mixture was washed with 1N HCl dried over MgSO4 then concentrated to give 18.7 g, (88%) of a N-Cyclopropyl-2-nitro-benzenesulfonamide as a tan solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06919331B2 |
| 출처 데이터셋 | uspto-grants-2005_07 |
| ORD ID | ord-56ffc089fbf04dcbbaa076fcefc8b31e |
| 출처 메모 | uspto-grants-2005_07 |