5-Hydroxyindole-2-carboxylic acid → 3-(Dimethylaminophenylmethyl)-5-hydroxy-1H-indole-2-carboxylic Acid

HRID 8985

반응식

HRID 8985 반응식
[OH:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6]([C:11]([OH:13])=[O:12])=[CH:5]2.[Cl-].[CH:15](=[N+:22]([CH3:24])[CH3:23])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[CH3:23][N:22]([CH:15]([C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:5]1[C:4]2[C:8](=[CH:9][CH:10]=[C:2]([OH:1])[CH:3]=2)[NH:7][C:6]=1[C:11]([OH:13])=[O:12])[CH3:24]

참가 물질

3

반응물 2

HCID 889585-Hydroxyindole-2-carboxylic acidHCID 11073839Methanaminium, N-methyl-N-(phenylmethylene)-, chloride

생성물 1

HCID 99445193-(Dimethylaminophenylmethyl)-5-hydroxy-1H-indole-2-carboxylic Acid

실험 절차

The preparation was carried out in accordance with general synthesis instructions 4 from 5-hydroxy-1H-indole-2-carboxylic acid and benzylidene-dimethyl-ammonium chloride, which had been prepared in accordance with example 1.

후처리

  1. customhad been prepared in accordance with example 1

출처 및 근거

ORD 기록
ord-e35ed87604f84e598d86fcf78697f08e
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07091220B2

연결된 노트

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