5-(phenylmethoxy)-1H-indole-2-carboxylic acid → 5-Benzyloxy-3-(dimethylaminophenylmethyl)-1H-indole-2-carboxylic Acid

HRID 8991노트

반응식

HRID 8991 반응식
[CH2:1]([O:8][C:9]1[CH:10]=[C:11]2[C:15](=[CH:16][CH:17]=1)[NH:14][C:13]([C:18]([OH:20])=[O:19])=[CH:12]2)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl-].[CH:22](=[N+:29]([CH3:31])[CH3:30])[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[CH2:1]([O:8][C:9]1[CH:10]=[C:11]2[C:15](=[CH:16][CH:17]=1)[NH:14][C:13]([C:18]([OH:20])=[O:19])=[C:12]2[CH:22]([N:29]([CH3:31])[CH3:30])[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 811465-(phenylmethoxy)-1H-indole-2-carboxylic acidHCID 11073839Methanaminium, N-methyl-N-(phenylmethylene)-, chloride

생성물 1

HCID 101356205-Benzyloxy-3-(dimethylaminophenylmethyl)-1H-indole-2-carboxylic Acid

실험 절차

The preparation was carried out in accordance with general synthesis instructions 4 from 5-benzyloxy-1H-indole-2-carboxylic acid and benzylidene-dimethyl-ammonium chloride, which had been prepared in accordance with example 1.

후처리

  1. customhad been prepared in accordance with example 1

출처 및 근거

ORD 기록
ord-a26ba1aa91024edd8cc9a52003c2eac1
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07091220B2

반응 노트

불러오는 중…