2-(3-Chloro-4-fluorophenyl)indole → {[2-(3-Chloro-4-fluorophenyl)-1H-indol-3-yl]-phenylmethyl}-dimethylamine

HRID 8993

반응식

HRID 8993 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[NH:10][C:11]3[C:16]([CH:17]=2)=[CH:15][CH:14]=[CH:13][CH:12]=3)[CH:5]=[CH:6][C:7]=1[F:8].[Cl-].[CH:19](=[N+:26]([CH3:28])[CH3:27])[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[NH:10][C:11]3[C:16]([C:17]=2[CH:19]([N:26]([CH3:28])[CH3:27])[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[CH:15][CH:14]=[CH:13][CH:12]=3)[CH:5]=[CH:6][C:7]=1[F:8]

참가 물질

3

반응물 2

HCID 27365772-(3-Chloro-4-fluorophenyl)indoleHCID 11073839Methanaminium, N-methyl-N-(phenylmethylene)-, chloride

생성물 1

HCID 10156554{[2-(3-Chloro-4-fluorophenyl)-1H-indol-3-yl]-phenylmethyl}-dimethylamine

실험 절차

The preparation was carried out in accordance with general synthesis instructions 4 from 2-(3-chloro-4-fluorophenyl)-1H-indole and benzylidene-dimethyl-ammonium chloride, which had been prepared in accordance with example 1.

후처리

  1. customhad been prepared in accordance with example 1

출처 및 근거

ORD 기록
ord-a14dcd750a5843378b734cc81f27f6c0
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07091220B2

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