Pent-3-yn-2-amine → HCID 67319087, 화합물
반응식
C(OC([NH:8][C:9]([CH3:36])([CH2:29][C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1)[CH2:10][O:11][CH2:12][C:13]1[CH:14]=[C:15]([CH:19]=[C:20]([C:22]2([C:27]#[N:28])[CH2:26][CH2:25][CH2:24][CH2:23]2)[CH:21]=1)[C:16]([OH:18])=O)=O)(C)(C)C.[CH3:37][CH:38]([NH2:42])[C:39]#[C:40][CH3:41]>>[NH2:8][C:9]([CH3:36])([CH2:29][C:30]1[CH:31]=[CH:32][CH:33]=[CH:34][CH:35]=1)[CH2:10][O:11][CH2:12][C:13]1[CH:14]=[C:15]([CH:19]=[C:20]([C:22]2([C:27]#[N:28])[CH2:26][CH2:25][CH2:24][CH2:23]2)[CH:21]=1)[C:16]([NH:42][CH:38]([C:39]#[C:40][CH3:41])[CH3:37])=[O:18]참가 물질
3
실험 절차
Prepared from 3-((2-tert-butoxycarbonylamino-2-methyl-3-phenylpropoxy)methyl)-5-(1-cyanocyclopentyl)benzoic acid and pent-3-yn-2-amine using a similar procedure as described for the preparation of Example 20. HRMS ES calculated for C29H35N3O2: 458.2802, found: 458.2813.
후처리
- customas described for the preparation of Example 20
출처 및 근거
- ORD 기록
- ord-22632e121edd4405aab64383515858a3