1-ethyl-2-phenyl-1H-indole → 3-[(2-Chlorophenyl)-piperidin-1-yl-methyl]-1-ethyl-2-phenyl-1H-indole

반응식

[CH2:1]([N:3]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH3:2].[Cl-].[Cl:19][C:20]1[CH:32]=[CH:31][CH:30]=[CH:29][C:21]=1[CH:22]=[N+:23]1[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]1>>[Cl:19][C:20]1[CH:32]=[CH:31][CH:30]=[CH:29][C:21]=1[CH:22]([N:23]1[CH2:28][CH2:27][CH2:26][CH2:25][CH2:24]1)[C:5]1[C:6]2[C:11](=[CH:10][CH:9]=[CH:8][CH:7]=2)[N:3]([CH2:1][CH3:2])[C:4]=1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

참가 물질

반응물 2

HCID 832481-ethyl-2-phenyl-1H-indole

HCID 179587471-(2-Chloro-benzylidene)-piperidinium chloride

생성물 1

HCID 102742193-[(2-Chlorophenyl)-piperidin-1-yl-methyl]-1-ethyl-2-phenyl-1H-indole

실험 절차

The preparation was carried out in accordance with general synthesis instructions 4 from 1-ethyl-2-phenyl-1H-indole and 1-(2-chloro-benzylidene)-piperidinium chloride

출처 및 근거

ORD 기록: ord-ff9a8d4fad55412297bdb1e95d7c1e2d
출처 데이터셋: uspto-grants-2006_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07091220B2

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