3-Chloro-N,N-dimethyl-1-propanamine → 3-[(Aminocarbonyl)amino]-5-{3-[3-(dimethylamino)propoxy]phenyl}-2-thiophenecarboxamide

HRID 900431노트

반응식

HRID 900431 반응식
[NH2:1][C:2]([NH:4][C:5]1[CH:9]=[C:8]([C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([OH:16])[CH:11]=2)[S:7][C:6]=1[C:17]([NH2:19])=[O:18])=[O:3].Cl[CH2:21][CH2:22][CH2:23][N:24]([CH3:26])[CH3:25]>>[NH2:1][C:2]([NH:4][C:5]1[CH:9]=[C:8]([C:10]2[CH:15]=[CH:14][CH:13]=[C:12]([O:16][CH2:21][CH2:22][CH2:23][N:24]([CH3:26])[CH3:25])[CH:11]=2)[S:7][C:6]=1[C:17]([NH2:19])=[O:18])=[O:3]

참가 물질

3

반응물 2

HCID 669603-Chloro-N,N-dimethyl-1-propanamineHCID 99654243-[(Aminocarbonyl)amino]-5-(3-hydroxyphenyl)-2-thiophenecarboxamide

생성물 1

HCID 99251783-[(Aminocarbonyl)amino]-5-{3-[3-(dimethylamino)propoxy]phenyl}-2-thiophenecarboxamide

실험 절차

Prepared by the method of Example 9(b) using the product of Example 6 and N-(3-chloropropyl)dimethylamine.

후처리

  1. customPrepared by the method of Example 9(b)

출처 및 근거

ORD 기록
ord-1dd2a9ee578c4ba999d4917b2f074ffe
출처 데이터셋
uspto-grants-2008_04
특허 번호
US07358376B2

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