1-ethyl-2-phenyl-1H-indole → 1-Ethyl-2-phenyl-3-(phenylpyrrolidin-1-yl-methyl)-1H-indole

반응식

[CH2:1]([N:3]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH3:2].[Cl-].[CH:19](=[N+:26]1[CH2:30][CH2:29][CH2:28][CH2:27]1)[C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1>>[CH2:1]([N:3]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([CH:19]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[N:26]2[CH2:27][CH2:28][CH2:29][CH2:30]2)=[C:4]1[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH3:2]

참가 물질

반응물 2

HCID 832481-ethyl-2-phenyl-1H-indole

HCID 109323601-Benzylidene-pyrrolidinium chloride

생성물 1

HCID 101344011-Ethyl-2-phenyl-3-(phenylpyrrolidin-1-yl-methyl)-1H-indole

실험 절차

The preparation was carried out in accordance with general synthesis instructions 4 from 1-ethyl-2-phenyl-1H-indole and 1-benzylidene-pyrrolidinium chloride.

출처 및 근거

ORD 기록: ord-26a143923e5c487886f1cf561a959abe
출처 데이터셋: uspto-grants-2006_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07091220B2

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