Potassium Carbonate → HCID 23117196, 화합물

HRID 900684노트

반응식

HRID 900684 반응식
C(=O)([O-])[O-].[K+].[K+].[Si:7]([O:14][CH2:15][CH2:16][CH2:17]Br)([C:10]([CH3:13])([CH3:12])[CH3:11])([CH3:9])[CH3:8].[Cl:19][C:20]1[CH:21]=[C:22]([CH:28]=[C:29]([F:32])[C:30]=1[OH:31])[C:23]([O:25][CH2:26][CH3:27])=[O:24]>CN(C=O)C>[Si:7]([O:14][CH2:15][CH2:16][CH2:17][O:31][C:30]1[C:29]([F:32])=[CH:28][C:22]([C:23]([O:25][CH2:26][CH3:27])=[O:24])=[CH:21][C:20]=1[Cl:19])([C:10]([CH3:13])([CH3:12])[CH3:11])([CH3:9])[CH3:8]

참가 물질

5

반응물 3

HCID 11430Potassium CarbonateHCID 607486(3-Bromopropoxy)(tert-butyl)dimethylsilaneHCID 23117176Ethyl 3-chloro-5-fluoro-4-hydroxybenzoate

생성물 1

HCID 23117196HCID 23117196, 화합물

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

반응 조건

온도
50 °C

실험 절차

Potassium carbonate and 3-(tert-butyldimethylsilyloxy)propyl bromide were added to a DMF solution of ethyl 3-chloro-5-fluoro-4-hydroxybenzoate, and the mixture was stirred at 50° C. to obtain ethyl 4-[3-(tert-butyldimethylsilyloxy)propoxy]-3-chloro-5-fluorobenzoate.

출처 및 근거

ORD 기록
ord-ad88a06897cb44aabef403317988ff6a
출처 데이터셋
uspto-grants-2008_04
특허 번호
US07361658B2

반응 노트

불러오는 중…