반응식
[NH:1]1[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.[F:7][C:8]1[CH:9]=[C:10]([CH:15]=[CH:16][C:17]=1F)[C:11]([O:13][CH3:14])=[O:12]>C1COCC1>[F:7][C:8]1[CH:9]=[C:10]([CH:15]=[CH:16][C:17]=1[N:1]1[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1)[C:11]([O:13][CH3:14])=[O:12]참가 물질
4
반응 조건
- 온도
- 60 °C
실험 절차
Anhydrous piperazine was added to a THF solution of methyl 3,4-difluorobenzoate, and the mixture was stirred at 60° C. for 18 hours to obtain methyl 3-fluoro-4-piperazin-1-ylbenzoate.
출처 및 근거
- ORD 기록
- ord-14289cc71cd6418a91293c16a9d87490
- 출처 데이터셋
- uspto-grants-2008_04
- 특허 번호
- US07361658B2
연결된 노트
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