Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-Amino-1,3,4-thiadiazole-2-sulfonamide → 7-Difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (5-sulfamoyl-[1,3,4]thiadiazol-2-yl)-amide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-Amino-1,3,4-thiadiazole-2-sulfonamide | HCID 84724 | — |
| 반응물 | 7-Difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid | HCID 66650268 | — |
| 생성물 | 7-Difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (5-sulfamoyl-[1,3,4]thiadiazol-2-yl)-amide | HCID 11995694 | — |
반응 단계
The title compound was prepared from 7-difluoromethyl-5-(4-trifluoromethyl-phenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxylic acid (example C. 1) and 5-amino-[1,3,4]thiadiazole-2-sulfonic acid amide [commercially available, CAS 14949-00-9] according to general procedure II.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07361659B2 |
| 출처 데이터셋 | uspto-grants-2008_04 |
| ORD ID | ord-004aacf72bfb40c99c7a652cd2dd38f3 |
| 출처 메모 | uspto-grants-2008_04 |