Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,3-Dihydrobenzo(b)furan-5-carboxylic acid → HCID 59698870, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,3-Dihydrobenzo(b)furan-5-carboxylic acid | HCID 676583 | — |
| 반응물 | 2-(2-Amino-thiazol-4-yl)-1-[4-(2-oxo-2-pyrrolidin-1-yl-ethyl)-piperazin-1-yl]-ethanone | HCID 59698840 | — |
| 생성물 | HCID 59698870 | HCID 59698870 | — |
반응 단계
In analogy to example 37.5, 2-(2-amino-thiazol-4-yl)-1-[4-(2-oxo-2-pyrrolidin-1-yl-ethyl)-piperazin-1-yl]-ethanone (example 37.4) was coupled with 2,3-dihydrobenzofurane-5-carboxylic acid, using general method D, to give 2,3-dihydro-benzofuran-5-carboxylic acid (4-{2-oxo-2-[4-(2-oxo-2-pyrrolidin-1-yl-ethyl)-piperazin-1-yl]-ethyl}-thiazol-2-yl)-amide. White solid. MS 506.5 ([M+Na]+)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07361672B2 |
| 출처 데이터셋 | uspto-grants-2008_04 |
| ORD ID | ord-3f92f6f55d954786a6f648aa0c0bd674 |
| 출처 메모 | uspto-grants-2008_04 |