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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 901090생성일: 2026년 10월 25일

1-Isopropylpiperidin-4-ol → 5-(1-isopropyl-piperidin-4-yloxy)-1H-indole-2-carboxylic acid

https://huagongshe.com/reaction/901090

반응식

참여 물질

역할이름HCID투입량
반응물1-Isopropylpiperidin-4-olHCID 79681—
반응물Ethyl 5-hydroxy-1H-indole-2-carboxylateHCID 90677—
반응물5-(1-Isopropyl-piperidin-4-yloxy)-1H-indole-2-carboxylic acid ethyl esterHCID 44185246—
생성물5-(1-isopropyl-piperidin-4-yloxy)-1H-indole-2-carboxylic acidHCID 59699456—

반응 단계

According to the procedure described for the synthesis of Example 5/step 1 5-(1-isopropyl-piperidin-4-yloxy)-1H-indole-2-carboxylic acid ethyl ester was synthesized from 5-hydroxy-1H-indole-2-carboxylic acid ethyl ester (commercially available) and 1-isopropyl-piperidin-4-ol (commercially available). The title compound was yielded in 33% as off-white solid. MS (m/e): 331.1 (MH+, 100%).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07361682B2
출처 데이터셋uspto-grants-2008_04
ORD IDord-3107c198f75b46f3b75c499866bceb56
출처 메모uspto-grants-2008_04