Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-[(Phenylmethoxy)carbonyl]-L-isoleucine → 2-(2-Methoxyphenyl)-8-(1-methylethyl)-5,6,7,8-tetrahydro-imidazo[1,2-a]pyrazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-[(Phenylmethoxy)carbonyl]-L-isoleucine | HCID 2724772 | — |
| 반응물 | 8-Butyl-7-(3-(imidazol-5-yl)-1-oxopropyl)-2-(2-methoxyphenyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine | HCID 22928232 | — |
| 생성물 | 2-(2-Methoxyphenyl)-8-(1-methylethyl)-5,6,7,8-tetrahydro-imidazo[1,2-a]pyrazine | HCID 22016811 | — |
반응 단계
through 5.g. were carried out in a manner analogous to Steps 1.c. through 1.f of example 1, starting with Cbz-(L)-Ile-OH in place of Cbz-(L)-Nle-OH, and yielding 2-(2-methoxyphenyl)-8-(1-methylethyl)-5,6,7,8-tetrahydro-imidazo[1,2-a]pyrazine (compound vii, where R3 is isobutyl, R4 is 2-methoxyphenyl and R5, R6, and R7 are H,).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07361656B2 |
| 출처 데이터셋 | uspto-grants-2008_04 |
| ORD ID | ord-fd194f83054845be845d9089738671af |
| 출처 메모 | uspto-grants-2008_04 |