2-Phenylindole → 3-[(2-methoxyphenyl)-pyrrolidin-1-yl-methyl]-2-phenyl-1H-indole

HRID 9014

반응식

HRID 9014 반응식
[C:1]1([C:7]2[NH:8][C:9]3[C:14]([CH:15]=2)=[CH:13][CH:12]=[CH:11][CH:10]=3)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl-].[CH3:17][O:18][C:19]1[CH:30]=[CH:29][CH:28]=[CH:27][C:20]=1[CH:21]=[N+:22]1[CH2:26][CH2:25][CH2:24][CH2:23]1>>[CH3:17][O:18][C:19]1[CH:30]=[CH:29][CH:28]=[CH:27][C:20]=1[CH:21]([N:22]1[CH2:26][CH2:25][CH2:24][CH2:23]1)[C:15]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[NH:8][C:7]=1[C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

3

반응물 2

HCID 136982-PhenylindoleHCID 179122531-(2-Methoxy-benzylidene)pyrrolidinium chloride

생성물 1

HCID 101779593-[(2-methoxyphenyl)-pyrrolidin-1-yl-methyl]-2-phenyl-1H-indole

실험 절차

The preparation was carried out in accordance with general synthesis instructions 4 from 2-phenyl-1H-indole and 1-(2-methoxy-benzylidene)-pyrrolidinium chloride, which had been prepared in accordance with example 24.

후처리

  1. customhad been prepared in accordance with example 24

출처 및 근거

ORD 기록
ord-0540e9ceb8d246e89cbdfe0484553734
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07091220B2

연결된 노트

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