4-Methylindole → 4-Methyl-3-(piperidin-1-yl-o-tolylmethyl)-1H-indole

HRID 9015

반응식

HRID 9015 반응식
[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH:4]=[CH:5][NH:6]2.[Cl-].[CH3:12][C:13]1[CH:25]=[CH:24][CH:23]=[CH:22][C:14]=1[CH:15]=[N+:16]1[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1>>[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[C:4]([CH:15]([N:16]1[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1)[C:14]1[CH:22]=[CH:23][CH:24]=[CH:25][C:13]=1[CH3:12])=[CH:5][NH:6]2

참가 물질

3

반응물 2

HCID 852824-MethylindoleHCID 179122571-(2-Methyl-benzylidene)-piperidinium chloride

생성물 1

HCID 99667754-Methyl-3-(piperidin-1-yl-o-tolylmethyl)-1H-indole

실험 절차

The preparation was carried out in accordance with general synthesis instructions 4 from 4-methyl-1H-indole and 1-(2-methyl-benzylidene)-piperidinium chloride, which had been prepared in accordance with example 30.

후처리

  1. customhad been prepared in accordance with example 30

출처 및 근거

ORD 기록
ord-196c1c862b4c4bf289afa7d0c7189a58
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07091220B2

연결된 노트

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