4-Methylindole → 3-[(2-methoxyphenyl)-pyrrolidin-1-yl-methyl]-4-methyl-1H-indole

HRID 9016

반응식

HRID 9016 반응식
[CH3:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]2[C:3]=1[CH:4]=[CH:5][NH:6]2.[Cl-].[CH3:12][O:13][C:14]1[CH:25]=[CH:24][CH:23]=[CH:22][C:15]=1[CH:16]=[N+:17]1[CH2:21][CH2:20][CH2:19][CH2:18]1>>[CH3:12][O:13][C:14]1[CH:25]=[CH:24][CH:23]=[CH:22][C:15]=1[CH:16]([N:17]1[CH2:21][CH2:20][CH2:19][CH2:18]1)[C:4]1[C:3]2[C:7](=[CH:8][CH:9]=[CH:10][C:2]=2[CH3:1])[NH:6][CH:5]=1

참가 물질

3

반응물 2

HCID 852824-MethylindoleHCID 179122531-(2-Methoxy-benzylidene)pyrrolidinium chloride

생성물 1

HCID 102680003-[(2-methoxyphenyl)-pyrrolidin-1-yl-methyl]-4-methyl-1H-indole

실험 절차

The preparation was carried out in accordance with general synthesis instructions 4 from 4-methyl-1H-indole and 1-(2-methoxy-benzylidene)-pyrrolidinium chloride, which had been prepared in accordance with example 24.

후처리

  1. customhad been prepared in accordance with example 24

출처 및 근거

ORD 기록
ord-4711fce3062541c49ba9870e83fae67d
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07091220B2

연결된 노트

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