2-Phenylindole → 3-[(2-Methoxyphenyl)-piperidin-1-yl-methyl]-2-phenyl-1H-indole

반응식

[C:1]1([C:7]2[NH:8][C:9]3[C:14]([CH:15]=2)=[CH:13][CH:12]=[CH:11][CH:10]=3)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl-].[CH3:17][O:18][C:19]1[CH:31]=[CH:30][CH:29]=[CH:28][C:20]=1[CH:21]=[N+:22]1[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1>>[CH3:17][O:18][C:19]1[CH:31]=[CH:30][CH:29]=[CH:28][C:20]=1[CH:21]([N:22]1[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1)[C:15]1[C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[NH:8][C:7]=1[C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

반응물 2

HCID 136982-Phenylindole

HCID 179122761-(2-Methoxy-benzylidene)-piperidinium chloride

생성물 1

HCID 102720863-[(2-Methoxyphenyl)-piperidin-1-yl-methyl]-2-phenyl-1H-indole

실험 절차

The preparation was carried out in accordance with general synthesis instructions 4 from 2-phenyl-1H-indole and 1-(2-methoxy-benzylidene)-piperidinium chloride.

출처 및 근거

ORD 기록: ord-85dcf7bc766249b39e1ff33b9cbbaf62
출처 데이터셋: uspto-grants-2006_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07091220B2

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