2-Phenyl-4-methylpentylamine → N-(2-Chloro-3-trifluoromethylbenzyl)-2-phenyl-4-methylpentylamine

HRID 902749

반응식

HRID 902749 반응식
[C:1]1([CH:7]([CH2:10][CH:11]([CH3:13])[CH3:12])[CH2:8][NH2:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[Cl:14][C:15]1[C:33]([C:34]([F:37])([F:36])[F:35])=[CH:32][CH:31]=[CH:30][C:16]=1[CH2:17]NCC(C1C=CC(OC)=CC=1)C>>[Cl:14][C:15]1[C:33]([C:34]([F:35])([F:36])[F:37])=[CH:32][CH:31]=[CH:30][C:16]=1[CH2:17][NH:9][CH2:8][CH:7]([C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)[CH2:10][CH:11]([CH3:13])[CH3:12]

참가 물질

3

반응물 2

HCID 207282122-Phenyl-4-methylpentylamineHCID 69254854N-(2-Chloro-3-trifluoromethylbenzyl)-2-(4-methoxyphenyl)propylamine

생성물 1

HCID 69253156N-(2-Chloro-3-trifluoromethylbenzyl)-2-phenyl-4-methylpentylamine수율 77%

실험 절차

The titled compound was prepared from 2-Phenyl-4-methylpentylamine in 77% yield in the same manner as the preparation of N-(2-Chloro-3-trifluoromethylbenzyl)-2-(4-methoxyphenyl)propylamine in Example 188d. MS (ESI) 370 (MH+)

출처 및 근거

ORD 기록
ord-937f1ad24ce844b69975ae6c0e83d414
출처 데이터셋
uspto-grants-2008_04
특허 번호
US07365085B2

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