6-Phenoxy-2-pyridinemethanol → Valine, N-[4-(trifluoromethyl)phenyl]-

HRID 903168노트

반응식

HRID 903168 반응식
[F:1][C:2]([F:20])([F:19])[C:3]1[CH:8]=[CH:7][C:6]([N:9]2[CH:13]([CH:14]([CH3:16])[CH3:15])[C:12](=[O:17])[O:11]C2=O)=[CH:5][CH:4]=1.O(C1N=C(CO)C=CC=1)C1C=CC=CC=1>>[F:1][C:2]([F:19])([F:20])[C:3]1[CH:8]=[CH:7][C:6]([NH:9][C@H:13]([C:12]([OH:17])=[O:11])[CH:14]([CH3:16])[CH3:15])=[CH:5][CH:4]=1

참가 물질

3

반응물 2

HCID 128791556-Phenoxy-2-pyridinemethanolHCID 204827863-(4-Trifluoromethylphenyl)-4-isopropyloxazolidine-2,5-dione

생성물 1

HCID 13388454Valine, N-[4-(trifluoromethyl)phenyl]-

실험 절차

In the same way, 3-(4-trifluoromethylphenyl)-4-isopropyloxazolidine-2,5-dione is reacted with (6-phenoxy-2-pyridyl)methanol to give the (6-phenoxy-2-pyridyl)methyl ester of N-(4-trifluoromethylphenyl)valine.

출처 및 근거

ORD 기록
ord-ef9e81c17416456aa030adb134e447ed
출처 데이터셋
uspto-grants-1980_10
특허 번호
US04226872

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