Boron trifluoride → 4,4,8-Trimethyl-9-methylene-bicyclo[3.3.1]nonan-6-one

HRID 903303노트

반응식

HRID 903303 반응식
[CH3:1][C:2]1[CH:3]([C:10](=[O:14])/[CH:11]=[CH:12]/[CH3:13])[C:4]([CH3:9])([CH3:8])[CH2:5][CH2:6][CH:7]=1.B(F)(F)F>C1C=CC=CC=1.CCOCC>[CH3:9][C:4]1([CH3:8])[CH:3]2[C:2](=[CH2:1])[CH:7]([CH:12]([CH3:13])[CH2:11][C:10]2=[O:14])[CH2:6][CH2:5]1

참가 물질

5

반응물 2

HCID 6356Boron trifluorideHCID 5366077(E)-1-(2,6,6-trimethylcyclohex-2-en-1-yl)but-2-en-1-one

생성물 1

HCID 233380624,4,8-Trimethyl-9-methylene-bicyclo[3.3.1]nonan-6-one

시약·촉매·용매 2

HCID 241Benzene용매HCID 3283Diethyl Ether용매2회

실험 절차

A solution of 2,6,6-trimethyl-1-crotonoyl-2-cyclohexene (1.0 g.) in a mixture of benzene and ether (10 ml.) was heated at ca. 80° in the presence of a catalytic amount of a saturated solution of BF3 in ether. The course of the reaction was followed by v.p.c. analysis. Three hours were usually necessary for converting the starting material into the bicyclic compound.

후처리

  1. customThree hours

출처 및 근거

ORD 기록
ord-96953c90447b47a983014c63a1cff3e8
출처 데이터셋
uspto-grants-1980_10
특허 번호
US04226892

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