Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Isopropylamine → N-Isopropylmethacrylamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Isopropylamine | HCID 6363 | — |
| 반응물 | Methyl Methacrylate | HCID 6658 | — |
| 촉매 | 2-Propanamine, hydrochloride (1:1) | HCID 6432137 | — |
| 생성물 | N-Isopropylmethacrylamide | HCID 83698 | 69.5% |
반응 단계
500 g (5 mols) of methyl methacrylate, 325 g (5.5 mols) of isopropylamine, and 12.4 g (0.13 mol) of isopropylamine hydrochloride were reacted in the presence of 0.03 mol of ferric acetylacetonate for 21/2 hours in a steel autoclave at 220° C. The pressure increased to a maximum of 18 atmospheres. The methyl methacrylate reacted to the extent of 80% and gave 442 g of N-isopropylmethacrylic acid amide (corresponding to a 68% yield referred to the methyl methacrylate used).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04228102 |
| 출처 데이터셋 | uspto-grants-1980_10 |
| ORD ID | ord-b6193f641d56497c9298501d403d530e |
| 출처 메모 | uspto-grants-1980_10 |