HCID 70596364, 화합물 → 2-(p-Biphenylyl)-2-penten-4-one

HRID 903526

반응식

HRID 903526 반응식
[C:1]1([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7](O)([CH3:12])[CH2:8][C:9](=[O:11])[CH3:10]>CO.O>[C:1]1([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7](=[CH:8][C:9](=[O:11])[CH3:10])[CH3:12]

참가 물질

4

반응물 1

HCID 70596364HCID 70596364, 화합물

생성물 1

HCID 545652342-(p-Biphenylyl)-2-penten-4-one

시약·촉매·용매 2

HCID 887Methanol용매HCID 962Water용매

반응 조건

온도
75 °C

실험 절차

To a 70° C. warm solution of 104.2 g 4-(p-biphenylyl)-4-hydroxypentan-2-one in a mixture of 450 ml methanol and 80 ml water 206 g ca. 65% sulphuric acid is added dropwise and the mixture is stirred 21/2 hours at 75° C. After cooling to 25° C. the resulting solid is filtered off, washed with water, then with diluted sodium hydroxide solution, again with water, dried and then recrystallised from toluene to give the title compound, m.p. 134°-136° C.

후처리

  1. additionis added dropwise
  2. temperatureAfter cooling to 25° C. the resulting solid
  3. filtrationis filtered off
  4. washwashed with water
  5. dry with materialwith diluted sodium hydroxide solution, again with water, dried
  6. customrecrystallised from toluene

출처 및 근거

ORD 기록
ord-17212dc0cefb4574add172e9b68bccb9
출처 데이터셋
uspto-grants-1980_10
특허 번호
US04228105

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