Ethanol → HCID 23335847, 화합물

HRID 904028노트

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HRID 904028 반응식
Cl[S:2]([CH:5]([C:9]1[CH:10]=[CH:11][C:12]2[O:16][CH2:15][CH2:14][C:13]=2[CH:17]=1)[C:6]([OH:8])=[O:7])(=[O:4])=[O:3].[CH2:18]([OH:20])[CH3:19].C(N(CC)CC)C.O>C(OCC)C>[CH2:18]([O:20][S:2]([CH:5]([C:9]1[CH:10]=[CH:11][C:12]2[O:16][CH2:15][CH2:14][C:13]=2[CH:17]=1)[C:6]([OH:8])=[O:7])(=[O:3])=[O:4])[CH3:19]

참가 물질

6

반응물 4

HCID 702EthanolHCID 962WaterHCID 8471TriethylamineHCID 23335839alpha-Chlorosulfonyl(2,3-dihydro-5-benzofuranyl)acetic acid

생성물 1

HCID 23335847HCID 23335847, 화합물

시약·촉매·용매 1

HCID 3283Diethyl Ether용매2회

반응 조건

온도
20 °C

실험 절차

α-Chlorosulfonyl(2,3-dihydro-5-benzofuranyl)acetic acid (5 mmole) is added to 30 ml of ethyl ether. To this mixture is added 5 mmole of ethanol in 10 ml of ethyl ether which contains 10 mmole of triethylamine. The mixture is stirred at 20° C. for about 1 hour and 50 ml of water is added. The pH is adjusted to about 6.5 and the layers separated. The organic layer is dried over magnesium sulfate, filtered and evaporated to give α-ethoxysulfonyl(2,3-dihydro-5-benzofuranyl)acetic acid.

후처리

  1. customthe layers separated
  2. dry with materialThe organic layer is dried over magnesium sulfate
  3. filtrationfiltered
  4. customevaporated

출처 및 근거

ORD 기록
ord-9d335cd22e5647139676fd2f35ab14c9
출처 데이터셋
uspto-grants-1980_10
특허 번호
US04229575

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