Timonacic → 3-[4-(4-Pentadecenylamino)benzoyl]-4-carboxythiazolidine

HRID 904499

반응식

HRID 904499 반응식
[CH2:1]([NH:16][C:17]1[CH:34]=[CH:33][C:20]([C:21]([N:23]2[CH:27]([C:28]([O:30]CC)=[O:29])[CH2:26][S:25][CH2:24]2)=[O:22])=[CH:19][CH:18]=1)[CH2:2][CH2:3][CH:4]=[CH:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15].S1CC(C(O)=O)NC1>C(=O)(O)[O-].[Na+].CC(C)=O>[CH2:1]([NH:16][C:17]1[CH:18]=[CH:19][C:20]([C:21]([N:23]2[CH:27]([C:28]([OH:30])=[O:29])[CH2:26][S:25][CH2:24]2)=[O:22])=[CH:33][CH:34]=1)[CH2:2][CH2:3][CH:4]=[CH:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15]

참가 물질

4

반응물 2

HCID 9934TimonacicHCID 536530283-[4-(4-Pentadecenylamino)benzoyl]-4-carboethoxythiazolidine

생성물 1

HCID 538355243-[4-(4-Pentadecenylamino)benzoyl]-4-carboxythiazolidine

시약·촉매·용매 1

HCID 86737261Acetone sodium bicarbonate용매

실험 절차

By means of the alkaline hydrolysis method of Example 2 the ethyl ester of Example 385 is converted to the subject carboxylic acid. This acid is also prepared using the procedure of Example 385 except that the acylation of the thiazolidine-4-carboxylic acid is carried out in aqueous acetone sodium bicarbonate solution.

후처리

  1. customThis acid is also prepared

출처 및 근거

ORD 기록
ord-a25f4f14ee584281bdb91b5e95b0134e
출처 데이터셋
uspto-grants-1980_10
특허 번호
US04230878

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