Amino 4-methylbenzene-1-sulfonate → HCID 14155665, 화합물

HRID 904619노트

반응식

HRID 904619 반응식
[Cl:1][C:2]1[CH:19]=[CH:18][C:5]([C:6]([C:8]2[N:9]=[CH:10][C:11]3[C:16]([CH:17]=2)=[CH:15][CH:14]=[CH:13][CH:12]=3)=[O:7])=[CH:4][CH:3]=1.[C:20]1([CH3:31])[CH:25]=[CH:24][C:23]([S:26]([O:29][NH2:30])(=[O:28])=[O:27])=[CH:22][CH:21]=1>ClCCl>[C:20]1([CH3:31])[CH:21]=[CH:22][C:23]([S:26]([O-:29])(=[O:27])=[O:28])=[CH:24][CH:25]=1.[NH2:30][N+:9]1[C:8]([C:6](=[O:7])[C:5]2[CH:4]=[CH:3][C:2]([Cl:1])=[CH:19][CH:18]=2)=[CH:17][C:16]2[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=2)[CH:10]=1

참가 물질

4

반응물 2

HCID 10965249Amino 4-methylbenzene-1-sulfonateHCID 141556643-(4-Chlorobenzoyl)-isoquinoline

생성물 1

HCID 14155665HCID 14155665, 화합물수율 73%

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

5 g (19 millimoles) of 3-(4-chlorobenzoyl)-isoquinoline are dissolved in 10 ml of dichloromethane, then 4 g (22 millimoles) of O-(p-toluenesulfonyl)-hydroxylamine are added, and the mixture is allowed to stand for an hour. 6 g (73%) of 2-amino-3-(4-chlorobenzoyl)-isoquinolinium-p-toluene sulfonate are obtained.

후처리

  1. waitto stand for an hour

출처 및 근거

ORD 기록
ord-bc75ea07737a4fc7adef028d27fa9fe3
출처 데이터셋
uspto-grants-1983_12
특허 번호
US04419355

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