4-(Chloromethyl)-1,3-thiazole → 2-Hydroxy-N-{2-[(4-{[3-methyl-4-(1,3-thiazol-4-ylmethoxy)phenyl]amino}quinazolin-5-yl)oxy]ethyl}acetamide

HRID 90478

반응식

HRID 90478 반응식
[Cl:1][CH2:2][c:3]1[n:4][cH:5][s:6][cH:7]1.[OH:8][CH2:9][C:10](=[O:11])[NH:12][CH2:13][CH2:14][O:15][c:16]1[c:17]2[c:18]([NH:26][c:27]3[cH:28][c:29]([CH3:34])[c:30]([OH:33])[cH:31][cH:32]3)[n:19][cH:20][n:21][c:22]2[cH:23][cH:24][cH:25]1>>[CH2:2]([c:3]1[n:4][cH:5][s:6][cH:7]1)[O:33][c:30]1[c:29]([CH3:34])[cH:28][c:27]([NH:26][c:18]2[c:17]3[c:16]([O:15][CH2:14][CH2:13][NH:12][C:10]([CH2:9][OH:8])=[O:11])[cH:25][cH:24][cH:23][c:22]3[n:21][cH:20][n:19]2)[cH:32][cH:31]1

참가 물질

3

반응물 2

HCID 27632904-(Chloromethyl)-1,3-thiazoleHCID 690609102-hydroxy-N-[2-({4-[(4-hydroxy-3-methylphenyl)amino]quinazolin-5-yl}oxy)ethyl]acetamide

생성물 1

HCID 113747212-Hydroxy-N-{2-[(4-{[3-methyl-4-(1,3-thiazol-4-ylmethoxy)phenyl]amino}quinazolin-5-yl)oxy]ethyl}acetamide

출처 및 근거

ORD 기록
ord-f39fe2ed9f0c43c7a05a17b776fffd8f
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

연결된 노트

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