Sodium Bicarbonate → HCID 178502658, 화합물
반응식
[C:1]([CH2:6][N:7]1[C:11]([SH:12])=[N:10][N:9]=[N:8]1)([C:3]([OH:5])=[O:4])=O.Cl.[CH3:14][O:15][NH2:16].C(=O)(O)[O-].[Na+]>O>[C:3]([C:1](=[N:16][O:15][CH3:14])[CH2:6][N:7]1[C:11]([SH:12])=[N:10][N:9]=[N:8]1)([OH:5])=[O:4]참가 물질
5
실험 절차
A solution of 1-oxalomethyl-1H-tetrazole-5-thiol (1.09 g) and methoxyamine hydrochloride (0.47 g) in water (15 ml) was adjusted to pH 6.5 with sodium bicarbonate and stirred at room temperature for 2 hours. After washing with ethyl acetate, the aqueous solution was adjusted to pH 1.8 with 10% hydrochloric acid, extracted with ethyl acetate, dried over magnesium sulfate and evaporated to give 1-(2-carboxy-2-methoxyiminoethyl)-1H-tetrazole-5-thiol (1.05 g), mp 84° to 86° C.
후처리
- washAfter washing with ethyl acetate
- extractionextracted with ethyl acetate
- dry with materialdried over magnesium sulfate
- customevaporated
출처 및 근거
- ORD 기록
- ord-41f4381c4958476cb0df20ccc7d908e2
- 출처 데이터셋
- uspto-grants-1983_12
- 특허 번호
- US04420477
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