Novoldiamine → Chloroquine

HRID 905109

반응식

HRID 905109 반응식
[Cl:1][C:2]1[CH:11]=[C:10]2[C:5]([C:6](=O)[CH2:7][CH2:8][NH:9]2)=[CH:4][CH:3]=1.[CH2:13]([N:15]([CH2:22][CH3:23])[CH2:16][CH2:17][CH2:18][CH:19]([NH2:21])[CH3:20])[CH3:14]>>[CH3:14][CH2:13][N:15]([CH2:16][CH2:17][CH2:18][CH:19]([NH:21][C:6]1[CH:7]=[CH:8][N:9]=[C:10]2[CH:11]=[C:2]([Cl:1])[CH:3]=[CH:4][C:5]=12)[CH3:20])[CH2:22][CH3:23]

참가 물질

3

반응물 2

HCID 78953NovoldiamineHCID 889747-Chloro-2,3-dihydro-4-quinolone

생성물 1

HCID 2719Chloroquine

실험 절차

17.8 millimols, representing a yield (determined) of 99% relative to the 7-chloro-1,2,3,4-tetrahydroquinolin-4-one converted, and of 96.3% relative to the 1-diethylamino-4-aminopentane converted, and

출처 및 근거

ORD 기록
ord-3705861b338d4c8c949fcc47b860aff8
출처 데이터셋
uspto-grants-1983_12
특허 번호
US04421920

연결된 노트

불러오는 중…