Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-{[1,1-Dimethyl-2-(2-phenoxyacetamido)ethyl]amino}-2'-chloro-3',4'-bis(benzyloxy)acetophenone hydrobromide → 1,1-Dimethyl-2-(2-phenoxyacetamido)ethylamine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-{[1,1-Dimethyl-2-(2-phenoxyacetamido)ethyl]amino}-2'-chloro-3',4'-bis(benzyloxy)acetophenone hydrobromide | HCID 20446758 | — |
| 반응물 | 2-{[1,1-Dimethyl-2-(2-phenoxyacetamido)ethyl]amino}-2'-chloro-3',4'-dihydroxy acetophenone hydrobromide | HCID 20446802 | — |
| 생성물 | 1,1-Dimethyl-2-(2-phenoxyacetamido)ethylamine | HCID 11806274 | — |
| 생성물 | 3,4-Dibenzyloxyphenacyl bromide | HCID 12681802 | — |
반응 단계
The above acetophenone derivative (A) was itself prepared in 85% yield, as a solid m.p. 141°-143° C. by a similar procedure to that described for the equivalent starting material in Example 11, but from 2-{[1,1-dimethyl-2-(2-phenoxyacetamido)ethyl]amino}-2'-chloro-3',4'-bis(benzyloxy)acetophenone hydrobromide. The latter compound was itself obtained in 40% yield as a solid, m.p. 61°-63° C., from N-(2-amino-2-methylpropyl)-2-phenoxyacetamide and 2-bromo-3',4'-bis(benzyloxy)acetophenone using a procedure similar to that in Example 11.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04423070 |
| 출처 데이터셋 | uspto-grants-1983_12 |
| ORD ID | ord-ebb36d08f9ca4acd92be7f997a9ed781 |
| 출처 메모 | uspto-grants-1983_12 |