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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 905300생성일: 2026년 10월 25일

2-{[1,1-Dimethyl-2-(2-phenoxyacetamido)ethyl]amino}-2'-chloro-3',4'-bis(benzyloxy)acetophenone hydrobromide → 1,1-Dimethyl-2-(2-phenoxyacetamido)ethylamine

https://huagongshe.com/reaction/905300

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참여 물질

역할이름HCID투입량
반응물2-{[1,1-Dimethyl-2-(2-phenoxyacetamido)ethyl]amino}-2'-chloro-3',4'-bis(benzyloxy)acetophenone hydrobromideHCID 20446758—
반응물2-{[1,1-Dimethyl-2-(2-phenoxyacetamido)ethyl]amino}-2'-chloro-3',4'-dihydroxy acetophenone hydrobromideHCID 20446802—
생성물1,1-Dimethyl-2-(2-phenoxyacetamido)ethylamineHCID 11806274—
생성물3,4-Dibenzyloxyphenacyl bromideHCID 12681802—

반응 단계

The above acetophenone derivative (A) was itself prepared in 85% yield, as a solid m.p. 141°-143° C. by a similar procedure to that described for the equivalent starting material in Example 11, but from 2-{[1,1-dimethyl-2-(2-phenoxyacetamido)ethyl]amino}-2'-chloro-3',4'-bis(benzyloxy)acetophenone hydrobromide. The latter compound was itself obtained in 40% yield as a solid, m.p. 61°-63° C., from N-(2-amino-2-methylpropyl)-2-phenoxyacetamide and 2-bromo-3',4'-bis(benzyloxy)acetophenone using a procedure similar to that in Example 11.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US04423070
출처 데이터셋uspto-grants-1983_12
ORD IDord-ebb36d08f9ca4acd92be7f997a9ed781
출처 메모uspto-grants-1983_12