Triethylamine → Methanesulphonylpyrazoline
반응식
[CH3:1][S:2](Cl)(=[O:4])=[O:3].[NH:6]1[CH2:10][CH:9]=[CH:8][NH:7]1.C(N(CC)CC)C>C(Cl)Cl>[CH3:1][S:2]([N:7]1[CH2:8][CH:9]=[CH:10][NH:6]1)(=[O:4])=[O:3]참가 물질
5
실험 절차
114.5 g of methanesulphonic acid chloride were added dropwise to 70 g of pyrazoline and 101 g of triethylamine in 300 ml of methylene chloride at room temperature. The mixture was subsequently stirred at room temperature for 3 hours and was filtered. The filtrate was washed with water, dried over sodium sulphate and concentrated. 114 g (77% of theory) of methanesulphonylpyrazoline of melting point 62° C. were obtained.
후처리
- filtrationwas filtered
- washThe filtrate was washed with water
- dry with materialdried over sodium sulphate
- concentrationconcentrated
출처 및 근거
- ORD 기록
- ord-a07ead0b1aaa4c1bb2f33c4ae7d2feac
- 출처 데이터셋
- uspto-grants-1983_12
- 특허 번호
- US04423225
반응 노트
불러오는 중…