Trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acid → trans-3-(2,2-Dichlorovinyl)-2,2-dimethylcyclopropylcarbonyl chloride

HRID 905382노트

반응식

HRID 905382 반응식
[Cl:1][C:2]([Cl:12])=[CH:3][C@H:4]1[C@H:6]([C:7](O)=[O:8])[C:5]1([CH3:11])[CH3:10].C(Cl)(=O)C([Cl:16])=O>C1(C)C=CC=CC=1>[Cl:1][C:2]([Cl:12])=[CH:3][C@H:4]1[C@H:6]([C:7]([Cl:16])=[O:8])[C:5]1([CH3:11])[CH3:10]

참가 물질

4

반응물 2

HCID 41539Trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylic acidHCID 65578Oxalyl chloride

생성물 1

HCID 11009700trans-3-(2,2-Dichlorovinyl)-2,2-dimethylcyclopropylcarbonyl chloride수율 94.5%

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

In a manner similar to Example 13A, the reaction of 25.0 g (0.12 mole) of (+)-trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic acid, 180 ml of toluene, and 30.4 g (0.24 mole) of oxalyl chloride gave 25.8 g of (+)-trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarbonyl chloride. The nmr spectrum was consistent with the proposed structure.

출처 및 근거

ORD 기록
ord-2a5c11d847224a2b81bb3397bf13c348
출처 데이터셋
uspto-grants-1983_12
특허 번호
US04423255

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