Dimethylamine → 3-[(2,3-Dimethoxy-phenyl)-dimethylamino-methyl]-4,7-dihydro-1H-indole-6-carboxylic Acid

HRID 9055

반응식

HRID 9055 반응식
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([C:10]([OH:12])=[O:11])[CH:8]=2)[CH:3]=[CH:2]1.[Cl-].[CH3:14][O:15][C:16]1[C:25]([O:26][CH3:27])=[CH:24][CH:23]=[CH:22][C:17]=1[CH:18]=[N+:19]([CH3:21])[CH3:20].COC1C(OC)=CC=CC=1C=O.CNC>>[CH3:14][O:15][C:16]1[C:25]([O:26][CH3:27])=[CH:24][CH:23]=[CH:22][C:17]=1[CH:18]([N:19]([CH3:21])[CH3:20])[C:3]1[C:4]2[CH2:5][CH:6]=[C:7]([C:10]([OH:12])=[O:11])[CH2:8][C:9]=2[NH:1][CH:2]=1

참가 물질

5

실험 절차

The preparation was carried out in accordance with general synthesis instructions 4 from 1H-indole-6-carboxylic acid and (2,3-dimethoxy-benzylidene)-dimethylammonium chloride, which had been prepared in accordance with example 44 from 2,3-dimethoxy-benzaldehyde and dimethylamine.

출처 및 근거

ORD 기록
ord-354e6617f7a94d3ab81859a0b3502e64
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07091220B2

연결된 노트

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