Cyclopropylmethanesulphonyl chloride → HCID 67385033, 화합물

HRID 906017노트

반응식

HRID 906017 반응식
Cl.Cl.[NH:3]1[CH2:8][CH2:7][CH2:6][CH:5]([NH:9][C:10]([NH:12][C:13]2[N:14]=[C:15]3[CH:21]=[CH:20][N:19]([CH2:22][O:23][CH2:24][CH2:25][Si:26]([CH3:29])([CH3:28])[CH3:27])[C:16]3=[N:17][CH:18]=2)=[O:11])[CH2:4]1.[CH:30]1([CH2:33][S:34](Cl)(=[O:36])=[O:35])[CH2:32][CH2:31]1>>[CH:30]1([CH2:33][S:34]([N:3]2[CH2:8][CH2:7][CH2:6][CH:5]([NH:9][C:10]([NH:12][C:13]3[N:14]=[C:15]4[CH:21]=[CH:20][N:19]([CH2:22][O:23][CH2:24][CH2:25][Si:26]([CH3:29])([CH3:28])[CH3:27])[C:16]4=[N:17][CH:18]=3)=[O:11])[CH2:4]2)(=[O:36])=[O:35])[CH2:32][CH2:31]1

참가 물질

3

반응물 2

HCID 14106996Cyclopropylmethanesulphonyl chlorideHCID 673855901-piperidin-3-yl-3-[5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]-urea dihydrochloride

생성물 1

HCID 67385033HCID 67385033, 화합물

실험 절차

1-(1-Cyclopropylmethanesulfonyl-piperidin-3-yl)-3-[5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]-urea was prepared in the same manner from 1-piperidin-3-yl-3-[5-(2-trimethylsilanyl-ethoxymethyl)-5H-pyrrolo[2,3-b]pyrazin-2-yl]-urea dihydrochloride and cyclopropyl-methanesulfonyl chloride.

출처 및 근거

ORD 기록
ord-714fa4c00df446dd9820816fcf6a799a
출처 데이터셋
uspto-grants-2011_09
특허 번호
US08012974B2

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