N-(3-fluorophenyl)piperidin-4-amine → N-(2-fluorophenyl)piperidin-4-amine

HRID 906351노트

반응식

HRID 906351 반응식
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[NH:8][CH:9]1[CH2:14][CH2:13][N:12](C(OC(C)(C)C)=O)[CH2:11][CH2:10]1.FC1C=C(NC2CCNCC2)C=CC=1>>[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[NH:8][CH:9]1[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]1

참가 물질

3

반응물 2

HCID 4778195N-(3-fluorophenyl)piperidin-4-amineHCID 43652152Tert-butyl 4-[(2-fluorophenyl)amino]piperidine-1-carboxylate

생성물 1

HCID 4778194N-(2-fluorophenyl)piperidin-4-amine

실험 절차

The title compound was prepared from 1,1-dimethylethyl 4-[(2-fluorophenyl)amino]-1-piperidinecarboxylate (D15) using a method similar to that described for D4 in Description 4.

출처 및 근거

ORD 기록
ord-8ece05a83bc84fe19ff1c3db5ba1ee67
출처 데이터셋
uspto-grants-2011_09
특허 번호
US08012981B2

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