Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 3-[(Pyridin-3-ylmethyl)-amino]-phthalic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 3-[(Pyridin-3-ylmethyl)-amino]-phthalic acid dimethyl ester | HCID 21040136 | — |
| 반응물 | 3-(2-Methoxy-ethylamino)-phthalic acid | HCID 21988519 | — |
| 생성물 | 3-[(Pyridin-3-ylmethyl)-amino]-phthalic acid | HCID 21988621 | — |
반응 단계
3-[(Pyridin-3-ylmethyl)-amino]-phthalic acid dimethyl ester (0.91 g, 3.03 mmol) was treated in the same manner as described above for the synthesis of 3-(2-methoxy-ethylamino)-phthalic acid except the pH of crude reaction mixture was adjusted to 2-3 by dropwise addition of concentrated HCl. The solvent was then evaporated in vacuo leaving a dry salt mixture that was used without further purification.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08012997B2 |
| 출처 데이터셋 | uspto-grants-2011_09 |
| ORD ID | ord-2601699a997842769bb7b4f0ab1a1fea |
| 출처 메모 | uspto-grants-2011_09 |