HCID 59273074, 화합물 → (2S,3S)-3-ethyl-2-isopropylpyrrolidin-3-ol

HRID 906963노트

반응식

HRID 906963 반응식
[CH2:1]([C@:3]1([OH:21])[CH2:7][CH2:6][N:5](C(OCC2C=CC=CC=2)=O)[C@H:4]1[CH:18]([CH3:20])[CH3:19])[CH3:2]>[Pd].O>[CH2:1]([C@:3]1([OH:21])[CH2:7][CH2:6][NH:5][C@H:4]1[CH:18]([CH3:20])[CH3:19])[CH3:2]

참가 물질

4

반응물 1

HCID 59273074HCID 59273074, 화합물

생성물 1

HCID 59273069(2S,3S)-3-ethyl-2-isopropylpyrrolidin-3-ol

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 962Water용매

실험 절차

By an operation in the same manner as in Reference Example 4 and using benzyl (2S,3S)-3-ethyl-3-hydroxy-2-isopropylpyrrolidine-1-carboxylate (2.2 g) and 50% water containing-10% Pd/C (0.11 g), the title compound was obtained as a colorless solid (yield: 1.33 g, yield: 83%).

출처 및 근거

ORD 기록
ord-d832021d577e4c1d8f5def85e928b879
출처 데이터셋
uspto-grants-2011_09
특허 번호
US08013008B2

반응 노트

불러오는 중…