HCID 59273087, 화합물 → (2S,3S)-2-ethyl-3-methylpyrrolidin-3-ol

HRID 906969노트

반응식

HRID 906969 반응식
[CH2:1]([C@H:3]1[C@:7]([OH:9])([CH3:8])[CH2:6][CH2:5][N:4]1C(OCC1C=CC=CC=1)=O)[CH3:2]>[Pd].O>[CH2:1]([C@H:3]1[C@@:7]([CH3:8])([OH:9])[CH2:6][CH2:5][NH:4]1)[CH3:2]

참가 물질

4

반응물 1

HCID 59273087HCID 59273087, 화합물

생성물 1

HCID 59273072(2S,3S)-2-ethyl-3-methylpyrrolidin-3-ol

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 962Water용매

실험 절차

By an operation in the same manner as in Reference Example 4 and using benzyl (2S,3S)-2-ethyl-3-hydroxy-3-methylpyrrolidine-1-carboxylate (2.84 g) and 50% water containing-10% Pd/C (0.31 g), the title compound was obtained as a colorless solid (yield: 1.77 g, yield: 88%).

출처 및 근거

ORD 기록
ord-ec331906123d4de4b4cb71e3626540d9
출처 데이터셋
uspto-grants-2011_09
특허 번호
US08013008B2

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