Dimethylamine → [(5-Chloro-1H-indol-3-yl)-m-tolyl-methyl]-dimethyl-amine

HRID 9070

반응식

[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[CH:5]2.[Cl-].[CH3:12][C:13]1[CH:14]=[C:15]([CH:20]=[CH:21][CH:22]=1)[CH:16]=[N+:17]([CH3:19])[CH3:18].CC1C=C(C=CC=1)C=O.CNC>>[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][CH:6]=[C:5]2[CH:16]([N:17]([CH3:18])[CH3:19])[C:15]1[CH:14]=[C:13]([CH3:12])[CH:22]=[CH:21][CH:20]=1

참가 물질

반응물 4

HCID 674Dimethylamine

HCID 121053-Methylbenzaldehyde

HCID 871105-Chloroindole

HCID 21985361(3-Methyl-benzylidene)-dimethylammonium chloride

생성물 1

HCID 21985311[(5-Chloro-1H-indol-3-yl)-m-tolyl-methyl]-dimethyl-amine

실험 절차

The preparation was carried out in accordance with general synthesis instructions 4 from 5-chloro-1H-indole and (3-methyl-benzylidene)-dimethylammonium chloride, which had been prepared in accordance with example 44 from 3-methyl-benzaldehyde and dimethylamine.

출처 및 근거

ORD 기록: ord-76c370c1664845558d3cc239ce3bf4b9
출처 데이터셋: uspto-grants-2006_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07091220B2

연결된 노트

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