Water → 2-(2-(Bis(2-hydroxyethyl)amino)-2-oxoethyl)dec-3-enoic acid

HRID 907247

반응식

HRID 907247 반응식
[NH:1]([CH2:5][CH2:6][OH:7])[CH2:2][CH2:3][OH:4].[CH:8]([CH:20]1[CH2:25][C:24](=[O:26])[O:23][C:21]1=[O:22])=[CH:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]CCCC.O>C1(C)C=CC=CC=1>[OH:4][CH2:3][CH2:2][N:1]([CH2:5][CH2:6][OH:7])[C:24](=[O:26])[CH2:25][CH:20]([CH:8]=[CH:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])[C:21]([OH:23])=[O:22]

참가 물질

5

반응물 3

HCID 962WaterHCID 8113Diethanolamine2회HCID 329333-(1-Dodecen-1-yl)dihydro-2,5-furandione

생성물 1

HCID 725398102-(2-(Bis(2-hydroxyethyl)amino)-2-oxoethyl)dec-3-enoic acid

시약·촉매·용매 1

HCID 1140Toluene용매2회

실험 절차

A 500 ml, two-neck flask was charged with 52.6 g (500 mmol) diethanolamine and 50 ml toluene. A temperature probe was placed into this solution through one of the necks of the flask and the flask was immersed into a water bath. A solution of 105.2 g (500 mmol) dodecenylsuccinic anhydride dissolved in 200 ml toluene was dripped into the magnetically stirred solution diethanolamine solution over a 40-minute period. Ice was added to the water bath as required to prevent temperature of the reaction mixture from getting above 25° C. The mixture was then stirred for another 2.5 hours at room temperature. The complete disappearance of the anhydride functional group was confirmed by infrared spectroscopy. The FTIR trace on this compound had significant absorptions at 2957, 2924, 2858, 1733, 1616, 1560, 1415, 1160, 1069, 969, and 728 wavenumbers. The solution was concentrated down to 50% solids in toluene and was then set aside for later use.

후처리

  1. customthe flask was immersed into a water bath
  2. customfrom getting above 25° C
  3. concentrationThe solution was concentrated down to 50% solids in toluene

출처 및 근거

ORD 기록
ord-81c3a10a6e46441dadd7ed913978c097
출처 데이터셋
uspto-grants-2011_09
특허 번호
US08013104B2

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