4-[4-Chloro-5-(2-chloroethyl)-6-(3-methoxyphenyl)-pyrimidin-2-yl]morpholine → 3-[7-(3-Dimethylamino-phenyl)-2-morpholin-4-yl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl]-phenol

반응식

[CH3:25][O:26][c:27]1[cH:28][c:29](-[c:33]2[c:34]3[c:35]([n:36][c:37]([N:39]4[CH2:40][CH2:41][O:42][CH2:43][CH2:44]4)[n:38]2)[N:45]([c:48]2[cH:49][c:50]([N:54]([CH3:55])[CH3:56])[cH:51][cH:52][cH:53]2)[CH2:46][CH2:47]3)[cH:30][cH:31][cH:32]1.[Cl:1][c:2]1[c:3]([CH2:4][CH2:5][Cl:6])[c:7](-[c:8]2[cH:9][cH:10][cH:11][c:12]([O:13][CH3:14])[cH:15]2)[n:16][c:17]([N:18]2[CH2:19][CH2:20][O:21][CH2:22][CH2:23]2)[n:24]1>>[OH:26][c:27]1[cH:28][c:29](-[c:33]2[c:34]3[c:35]([n:36][c:37]([N:39]4[CH2:40][CH2:41][O:42][CH2:43][CH2:44]4)[n:38]2)[N:45]([c:48]2[cH:49][c:50]([N:54]([CH3:55])[CH3:56])[cH:51][cH:52][cH:53]2)[CH2:46][CH2:47]3)[cH:30][cH:31][cH:32]1

참가 물질

반응물 2

HCID 592449884-[4-Chloro-5-(2-chloroethyl)-6-(3-methoxyphenyl)-pyrimidin-2-yl]morpholine

HCID 67387490{3-[4-(3-Methoxy-phenyl)-2-morpholin-4-yl-5,6-dihydro-pyrrolo[2,3-d]pyrimidin-7-yl]-phenyl}-dimethyl-amine

생성물 1

HCID 248890943-[7-(3-Dimethylamino-phenyl)-2-morpholin-4-yl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl]-phenol

출처 및 근거

ORD 기록: ord-8354a51897204e1abb987bae228668f5
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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