Morpholine → 2-Methyl-4-(morpholine-4-carbonyl)-2H-pyrazole-3-carboxylic acid (5-morpholin-4-yl-2-phenyl-imidazo[1,2-c]pyrimidin-7-yl)-amide
반응식
[NH:1]1[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[CH3:7][N:8]1[C:12]([C:13](=[O:36])[NH:14][C:15]2[N:20]=[C:19]([N:21]3[CH2:26][CH2:25][O:24][CH2:23][CH2:22]3)[N:18]3[CH:27]=[C:28]([C:30]4[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=4)[N:29]=[C:17]3[CH:16]=2)=[C:11]([C:37]([OH:39])=O)[CH:10]=[N:9]1>>[N:21]1([C:19]2[N:18]3[CH:27]=[C:28]([C:30]4[CH:31]=[CH:32][CH:33]=[CH:34][CH:35]=4)[N:29]=[C:17]3[CH:16]=[C:15]([NH:14][C:13]([C:12]3[N:8]([CH3:7])[N:9]=[CH:10][C:11]=3[C:37]([N:1]3[CH2:6][CH2:5][O:4][CH2:3][CH2:2]3)=[O:39])=[O:36])[N:20]=2)[CH2:22][CH2:23][O:24][CH2:25][CH2:26]1참가 물질
3
실험 절차
The title compound was prepared in analogy to Example 13, Step 2, using morpholine and 1-methyl-5-(5-morpholin-4-yl-2-phenyl-imidazo[1,2-c]pyrimidin-7-ylcarbamoyl)-1H-pyrazole-4-carboxylic acid. MS (m/e)=517.2 [M+H+].
출처 및 근거
- ORD 기록
- ord-e3edac6cf3274d83b8ca89aa828fb725
- 출처 데이터셋