Trifluoroacetic acid → HCID 59366526, 화합물

HRID 908656노트

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HRID 908656 반응식
[Cl:1][C:2]([Cl:23])=[CH:3][CH2:4][O:5][C:6]1[CH:20]=[C:19]([Cl:21])[C:9]([O:10][CH2:11][C:12]([O:14]C(C)(C)C)=[O:13])=[C:8]([Cl:22])[CH:7]=1.FC(F)(F)C(O)=O>C(Cl)Cl>[Cl:23][C:2]([Cl:1])=[CH:3][CH2:4][O:5][C:6]1[CH:7]=[C:8]([Cl:22])[C:9]([O:10][CH2:11][C:12]([OH:14])=[O:13])=[C:19]([Cl:21])[CH:20]=1

참가 물질

4

반응물 2

HCID 6422Trifluoroacetic acidHCID 59366522Tert-butyl 2-(4-(3,3-dichloroprop-2-enyloxy)-2,6-dichlorophenoxy)acetate

생성물 1

HCID 59366526HCID 59366526, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매2회

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온도
0 °C

실험 절차

A mixture of 0.3 gram (0.0008 mole) of tert-butyl 2-(4-(3,3-dichloroprop-2-enyloxy)-2,6-dichlorophenoxy)acetate in 3.0 mL of methylene chloride was stirred and cooled to 0° C. Trifluoroacetic acid (3.0 mL, 0.04 mole) was added and the reaction mixture was allowed to warm to ambient temperature where it stirred for two hours. The reaction mixture was concentrated under reduced pressure leaving a residue. The residue was dissolved in methylene chloride and the solution concentrated under reduced pressure and the resulting residue was dissolved in methylene chloride again. The solution was concentrated under reduced pressure to yield a quantitative amount of the subject compound as a white powder.

후처리

  1. temperatureto warm to ambient temperature where it
  2. stirringstirred for two hours
  3. concentrationThe reaction mixture was concentrated under reduced pressure
  4. customleaving a residue
  5. concentrationthe solution concentrated under reduced pressure
  6. dissolutionthe resulting residue was dissolved in methylene chloride again
  7. concentrationThe solution was concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-7c60a271ea024946a3ffb269a31a06e4
출처 데이터셋
uspto-grants-2011_09
특허 번호
US08017635B2

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