Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
BROMINE CHLORIDE (BrCl) → HCID 178421697, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | BROMINE CHLORIDE (BrCl) | HCID 61697 | — |
| 반응물 | 2-Amino-4-chlorobenzenesulphonamide | HCID 77790 | — |
| 반응물 | 3-Bromo-5-tert-butyl-6-hydroxy-2-methyl-benzoic acid phenyl ester | HCID 57421453 | — |
| 생성물 | HCID 178421697 | HCID 178421697 | — |
반응 단계
From 3-bromo-5-tert-butyl-6-hydroxy-2-methyl-benzoic acid phenyl ester and 2-amino-4-chlorobenzenesulfonamide; obtained as white crystals following column chromatography (silica gel/EtOAc-heptane-CH2Cl2 1:6:3); mp 270-271° C. (decomp., ebullition); 1H NMR (DMSO): δ 12.58 (s, 1H, NH), 9.64 (s, 1H), 7.91 (d, J=8.3 Hz, 1H), 7.55 (dd, J˜8.3, 1.9 Hz, 1H), 7.48 (s, 1H), 7.34 (d, J=1.9 Hz, 1H), 2.20 (s, 3H), 1.37 (s, 9H); LC-MS: m/z 457/459/461 (M+H; BrCl isotope pattern), 935/937/939/941 (2M+Na; Br2Cl2 isotope pattern); Rt=2.24 min.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08022066B2 |
| 출처 데이터셋 | uspto-grants-2011_09 |
| ORD ID | ord-d6c87c5a32994af2a75162acd1d17b94 |
| 출처 메모 | uspto-grants-2011_09 |