Ammonia → N-p-Bromophenylthiourea

HRID 910227

반응식

HRID 910227 반응식
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]=[C:9]=[S:10])=[CH:4][CH:3]=1.[NH3:11]>O1CCCC1>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]([NH2:11])=[S:10])=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 222AmmoniaHCID 161334-Bromophenyl isothiocyanate

생성물 1

HCID 2735620N-p-Bromophenylthiourea

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

4-Bromophenylisothiocyanate (21.4 g) was dissolved in tetrahydrofuran (50 mL), and concentrated aqueous ammonia (28%) (13.7 mL) was added dropwise to the solution, followed by stirring at room temperature for 10 minutes. The solvent was concentrated under reduced pressure, and the crystals were recovered through filtration by use of water, followed by recrystallization from ethanol, to thereby yield the title compound (16.4 g).

후처리

  1. concentrationThe solvent was concentrated under reduced pressure
  2. filtrationthe crystals were recovered through filtration by use of water
  3. customfollowed by recrystallization from ethanol

출처 및 근거

ORD 기록
ord-21dc0986b22b4059a3b8ea7a202da54c
출처 데이터셋
uspto-grants-2011_09
특허 번호
US08022075B2

연결된 노트

불러오는 중…