참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | 2-Amino-5-bromobenzene-1-thiol | HCID 1209045 | — |
| 반응물 | 4-(5-Oxazolyl)benzaldehyde | HCID 10583346 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 생성물 | 5-[4-(6-Bromo-1,3-benzothiazol-2-yl)phenyl]-1,3-oxazole | HCID 67405287 | 58.8% |
반응 단계
2 Amino-5-bromobenzenethiol (102 mg) and 4-(1,3-oxazol-5-yl)benzaldehyde (87 mg) were dissolved in dimethylsulfoxide (1 mL), followed by stirring at 160° C. for 10 minutes. Water (10 mL) was added to the reaction mixture. The precipitated matter was recovered through filtration, and washed with methanol, to thereby yield the title compound (105 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US08022075B2 |
|---|
| 출처 데이터셋 | uspto-grants-2011_09 |
|---|
| ORD ID | ord-0e754375d48d4d6aa7a3d6b803037183 |
|---|
| 출처 메모 | uspto-grants-2011_09 |
|---|
