Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,6-Dimethylphenol → 2-Chloro-4-(2,6-dimethylphenoxy)pyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,6-Dimethylphenol | HCID 11335 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 2-Chloro-4-nitropyridine | HCID 735152 | — |
| 생성물 | 2-Chloro-4-(2,6-dimethylphenoxy)pyridine | HCID 86634736 | 96.3% |
반응 단계
Using the method of Example 3, Step A, 2,6-dimethylphenol (0.771 g, 6.31 mmol), 60% sodium hydride in mineral oil (252 mg, 6.31 mmol), and 2-chloro-4-nitropyridine (1.00 g, 6.31 mmol) were reacted to provide 2-chloro-4-(2,6-dimethylphenoxy)pyridine (1.42 g, 96% yield) as a white solid. 1H NMR (CDCl3) δ 8.20 (d, 1H), 7.12 (s, 4H), 6.65-6.68 (m, 2H), 2.11 (s, 6H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08022222B2 |
| 출처 데이터셋 | uspto-grants-2011_09 |
| ORD ID | ord-4063f08ca8f346c7ad8604fa9a1f063c |
| 출처 메모 | uspto-grants-2011_09 |