N,N-Dimethylethylenediamine → HCID 86634755, 화합물
반응식
[ClH:1].[CH3:2][C:3]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=O)=[CH:5][C:4]=1[O:12][C:13]1[CH:18]=[CH:17][N:16]=[C:15]([NH:19][C:20]2[S:21][CH:22]=[C:23]([CH3:25])[N:24]=2)[CH:14]=1.[CH3:26][N:27]([CH3:31])[CH2:28][CH2:29][NH2:30]>>[ClH:1].[ClH:1].[CH3:26][N:27]([CH3:31])[CH2:28][CH2:29][NH:30][C:7](=[O:9])[C:6]1[CH:10]=[CH:11][C:3]([CH3:2])=[C:4]([O:12][C:13]2[CH:18]=[CH:17][N:16]=[C:15]([NH:19][C:20]3[S:21][CH:22]=[C:23]([CH3:25])[N:24]=3)[CH:14]=2)[CH:5]=1참가 물질
3
실험 절차
The title compound was prepared according to the method of Example 107 from 4-methyl-3-(2-(4-methylthiazol-2-ylamino)pyridin-4-yloxy)benzoic acid hydrochloride (Example 108) and N,N-dimethylethylenediamine. Yield: 0.065 g, 25%. 1H NMR (CDCl3), 8.84 (bs, 1H), 8.16 (d, 1H), 7.90 (d, 1H), 7.86 (bs, 1H), 7.37 (d, 1H), 6.80 (bs, 1H), 6.71 (dd, 1H), 6.38 (s, 1H), 3.89 (m, 2H), 3.35 (m, 2H), 2.91 (s, 6H), 2.37 (s, 3H), 2.22 (s, 3H).
출처 및 근거
- ORD 기록
- ord-55ee145dd2f84b838e91ff4e608d169d
- 출처 데이터셋
- uspto-grants-2011_09