Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetonitrile → HCID 59244915, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetonitrile | HCID 6342 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 반응물 | tert-Butyl piperazine-1-carboxylate | HCID 143452 | — |
| 반응물 | 3-Bromophenethyl bromide | HCID 14361216 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | HCID 59244915 | HCID 59244915 | 92.2% |
반응 단계
To 3-(2-bromo-ethyl)-1-bromo-benzene (0.15 ml, 1 mmol), 1-tert-butoxycarbonyl-piperazine (186 mg) and potassium carbonate (280 mg), acetonitrile (4 ml) was added, followed by stirring for 4 days. To the reaction mixture, ethyl acetate was added, which was washed with ammonium chloride solution, followed by drying over sodium sulfate. After filtering off the drying agent, the filtrate was concentrated under reduced pressure, to obtain 3-(2-(4-tert-butoxycarbonyl-piperazin-1-yl)-ethyl)-1-bromo-benzene as a colorless oil (340 mg, 92%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08022205B2 |
| 출처 데이터셋 | uspto-grants-2011_09 |
| ORD ID | ord-593da5778212483a84c2edee09c15c65 |
| 출처 메모 | uspto-grants-2011_09 |