Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Iodo-4-nitrobenzene → N-[3-(4-methylpiperazin-1-yl)propyl]-4-nitro-1-aminobenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Iodo-4-nitrobenzene | HCID 12495 | — |
| 반응물 | 1-(3-Aminopropyl)-4-methylpiperazine | HCID 78328 | — |
| 생성물 | N-[3-(4-methylpiperazin-1-yl)propyl]-4-nitro-1-aminobenzene | HCID 21975010 | — |
반응 단계
Using 1-iodo-4-nitro-benzene (500 mg) instead of 1-bromo-3-nitro-benzene, and 3-(4-methyl-piperazin-1-yl)-propylamine (379 mg) instead of morpholine, in the same manner as Step A in Example 1-D-105, the desired compound was obtained (432 mg, 77%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08022205B2 |
| 출처 데이터셋 | uspto-grants-2011_09 |
| ORD ID | ord-e4660a3f5af040859863afab87d5fd01 |
| 출처 메모 | uspto-grants-2011_09 |